Best Research Awards

Yuto Tei

Department of Ophthalmology, Toho University School of Medicine

「Pathogenic Mechanism of Dry Eye-Induced Chronic Ocular Pain and a Mechanism-Based Therapeutic Approach」
Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):7.

Research Awards

Fan Yang

Sun Yat-sen University

「Eyelid blood vessel and meibomian gland changes in a sclerodermatous chronic GVHD mouse model」
Ocul Surf. 2022 Oct;26:328-341.

Research Awards

Yuichi Okumura

Juntendo University Faculty of Medicine, Department of Ophthalmology

「Biological effects of stored platelet-rich plasma eye-drops in corneal wound healing」
Br J Ophthalmol. 2022 Sep 26;bjo-2022-322068.

Best Research Awards

Shinri Sato

Department of Ophthalmology Keio University School of medicine

「Positive Effects of Oral Antibiotic Administration in Murine Chronic Graft-versus-Host Disease」
Int J Mol Sci. 2021 Apr 3;22(7):3745.

Research Awards

Yutaka Sakurai

Department of Ophthalmology, National Defense Medical College

「Programmed Cell Death-1 Pathway Deficiency Enhances Autoimmunity Leading to Dacryoadenitis of Mice」
Am J Pathol. 2021 Jun;191(6):1077-1093.

Research Awards

Akiko Hanyuda

Department of Ophthalmology Keio University School of medicine

Department of Ophthalmology Keio University School of medicine 「Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study」
Ocul Surf. 2021 Jul;21:306-312.

Best Research Awards

Jin Kai

The Fifth Affiliated Hospital SUN YAT-SEN University

「Identification of Lacrimal Gland Postganglionic Innervation and Its Regulation of Tear Secretion」Am J Pathol. 2020 May;190(5):1068-1079

Research Awards

Mamoru Ogawa

Department of Ophthalmology Keio University School of medicine

「Eosinophils promote corneal wound healing via the 12/15-lipoxygenase pathway」FASEB J. 2020 Sep;34(9):12492-12501.

Research Awards

Yuka Hosotani

Department of Ophthalmology Hyogo College of Medicine

「Characteristics of tear abnormalities associated with benign essential blepharospasm and amelioration by means of botulinum toxin type A treatment」Jpn J Ophthalmol. 2020 Jan;64(1):45-53.

Best Research Awards

Takenori Inomata

Department of Ophthalmology, Juntendo University School of Medicine

「Characteristics and Risk Factors Associated With Diagnosed and Undiagnosed Symptomatic Dry Eye Using a Smartphone Application」JAMA Ophthalmol. 2020 Jan 1;138(1):58-68. doi: 10.1001/jamaophthalmol.2019.4815.

Research Awards

Yosuke Shikama

National Center for Geriatrics and Gerontology

「Involvement of Adiponectin in Age-Related Increases in Tear Production in Mice」Aging (Albany NY). 2019 Oct 8;11(19):8329-8346. doi: 10.18632/aging.102322. Epub 2019 Oct 8.

Research Awards

Akiko Hanyuda

Department of Ophthalmology Keio University School of medicine

「Physical Inactivity, Prolonged Sedentary Behaviors, and Use of Visual Display Terminals as Potential Risk Factors for Dry Eye Disease: JPHC-NEXT Study」Ocul Surf. 2020 Jan;18(1):56-63. doi: 10.1016/j.jtos.2019.09.007. Epub 2019 Sep 26.

Best Research Awards

Yoshiaki Tagawa

Department of Ophthalmology Faculty of Medicine and Graduate School of Medicine Hokkaido University

「Corneal hyperalgesia in patients with short tear film break-up time dry eye.」Ocul Surf. 2019 Jan;17(1):55-59. doi: 10.1016

Research Awards

Takayuki Itokawa

Department of Ophthalmology, Toho University Omori Medical Center

「Association Between Ocular Surface Temperature and Tear Film Stability in Soft Contact Lens Wearers.」Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):771-775. doi: 10.1167/iovs.17-23173.

Research Awards

Hideki Sonobe

Department of Ophthalmology Keio University School of medicine

「A novel and innovative paper-based analytical device for assessing tear lactoferrin of dry eye patients.」Ocul Surf. 2019 Jan;17(1):160-166. doi:10.1016/j.jtos.2018.11.001. Epub 2018 Nov 3.

Best Research Awards

Koji Kitazawa

North Medical Center, Kyoto Prefectural University of Medicine

「PAX6 regulates human corneal epithelium cell identity」 Exp Eye Res. 2017 Jan;154:30-38.

Research Awards

Minako Kaido

Department of Ophthalmology Keio University School of medicine

「Relation of accommodative microfluctuation with dry eye symptoms in short tear break-up time dry eye.」 PLoS One. 2017 Sep 8;12(9):e0184296.

Research Awards

Chi Hoang Viet Vu

Department of Ophthalmology Keio University School of medicine

「Influence of Meibomian Gland Dysfunction and Friction-Related Disease on the Severity of Dry Eye」Ophthalmology. 2018 Feb 16. pii: S0161-6420(17)32722-7.

Best Research Awards

Yuichi Uchino

Department of Ophthalmology Keio University School of medicine

「Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers.」Sci Rep. 2016 Jun 14;6:27699.

Research Awards

Minako Kaido

Department of Ophthalmology Keio University School of medicine

「Relationship of Corneal Pain Sensitivity With Dry Eye Symptoms in Dry Eye With Short Tear Break-Up Time.Exp Eye Res.」Invest Ophthalmol Vis Sci. 2016 Mar;57(3):914-9

Research Awards

Akihiro Higuchi

Research Promotion Institute,Oita University

「Selenium-binding lactoferrin is taken into corneal epithelial cells by a receptor and prevents corneal damage in dry eye model animals.」Sci Rep. 2016 Nov 11;6:36903.

Best Research Awards

Eriko Yoshioka

Department of Ophthalmology, Ehime Prefectural Central Hospital・ Yoshioka Eye Clinic

Influence of Eyelid Pressure on Fluorescein Staining of Ocular Surface in Dry Eyes

Research Awards

Masatoshi Hirayama

Department of Ophthalmology Keio University School of medicine

The changes in the expression profiles of cytokeratins in mouse lacrimal gland development

Research Awards

Chika Shigeyasu

Department of Ophthalmology, Kyorin University Hospital

Diquafosol Tetrasodium Increases the Concentration of Mucin-like Substances in Tears of Healthy Human Subjects. Diquafosol sodium ophthalmic solution for the treatment of dry eye: clinical evaluation and biochemical analysis of tear composition.

Best Research Awards

Mayumi Ueta

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine

IKZF1, a New Susceptibility Gene, for Cold Medicine-Related Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis with Severe Mucosal Involvement

Research Awards

Osama Ibrahim

Department of Ophthalmology Keio University School of medicine

Oxidative Stress Induced Age Dependent Meibomian Gland Dysfunction in Cu, Zn-ｓuperoxidedismutase-1(Sod1) Knockout Mice

Research Awards

Yuichi Uchino

Harvard Medical School,Schepens Eye Research Institute

Alteration of Tear Mucin 5AC in Office Workers Using Visual Display Terminals:The Osaka Study

Masatoshi Hirayama

Keio University School of Medicine

Functional lacrimal gland regeneration by transplanationof a bioengineered organ germ Nat Commun. 2013;4:2497

Saori Taniguchi

Keio University School of Medicine

Angiotensin II type 1 receptor antagonist attenuateslacrimal gland, lung, and liver fibrosis in amurine model of chronic graft-versus-host disease. PLoS One. 2013 Jun6;8(6):e64724.

Takashi Kojima

Keio University School of Medicine

Age-related dysfunction of the lacrimal gland and oxidative stress: evidence from the Cu,Zn-superoxide dismutase-1 (Sod 1) knockout mice. Am J pathol. 2012 May; 180(5):1879-96

Mizuka Kamoi

Keio University School of Medicine

Accumulation of secretory vesicles in the lacrimal gland epithelia is related to non-Sｊögren's type dry eye in visual display terminal users PLoS One. 2012;7(9):e43688

Osama Ibrahim

Keio University School of Medicine

The efficacy, sensitivity, and specificity of strip meniscometry in Conjunction with Tear Function Tests in the Assessment of Tear Meniscus. Invest Ophthalmol Vis Sci （IOVS）. 2011 Apr 6;52(5):2194-8.

Takashi Kojima

Japanese Red Cross Gifu Hospital

Effect of Controlled adverse chamber environment exposure on tear functions in silicon hydrogel and hydrogel soft contact lens wearers. Invest Ophthalmol Vis Sci （IOVS）. 2011 Nov 6;52(5):2194-8.

Motoko Kawashima

Keio University School of Medicine

Calorie restriction: A new therapeutic intervention for age-related dry eye disease in rats.

Akihiro Higuchi

Keio University School of Medicine

Selenoprotein P controls oxidative stress in cornea.

Yoko Ogawa

Keio University School of Medicine

Epithelial mesenchymal transition in human ocular chronic graft-versushost disease.

Tomoyuki Kamao

Ehime University School of Medicine

Genetic Dissociation of Dacryoadenitis and Sialadenitis in a Sjogren’s Syndrome Mouse Model with Common and Different Susceptibility Gene Loci.

Norihiko Yokoi

Kyoto Prefectual University of Medicine

Rheology of Tear Fim Lipid Layer Spread in Normal and Aqueous Tear-Deficient Dry eyes.

Reiko Arita

Itoh Hospital/The University of Tokyo

Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population.

Hideki Goto

Tsurumi University

Tear Evaporation Rates in Sjogren Syndrome and non-Sjogren Dry Eye Patients.

Hiroshi Toshida

Juntendo University

Evaluation of novel dry eye model: pre-ganglionic parasympatheric denervation in rabbit.

Shizuka Koh

University of Rochester / Osaka University

Serial Measurements of Higher-order Aberrations after Blinking in Normal Subjects.

Murat Dogru

Keio University School of Medicine

Strip Meniscometry:A New and Simple Method of Tear Meniscus Evaluation.

Shigeru Nakamura

Ophtecs Corporation Research Center

D-beta-hydroxybutyrate protects against corneal epithelial disorders in a rat dry eye model with jogging board.

Yoko Ogawa

Keio University School of Medicine

Donor fibroblast chimerism in the pathogenic fibrotic lesion of human chronic graft-versus-host disease.

Yuichi Hori

Osaka University

Differential regulation of membrane-associated mucins in the human ocular surface epithelium.
Invest Ophthalmol Vis Sci. 2004;45:112-122

Kunio Maruyama

Kyoto Prefectual University of Medicine

Effect of environmental conditions of tear dynamics in soft contact lens wearers.